Antibiotic drug design is facilitated when an enzyme that is essential to the pathogen's survival is absent or very different in humans.
Bewertung:metabolic pathways are not just regulated through inhibition since enzyme activation is equally important.
Bewertung:Natural enzyme inhibitors can also be poisons and are used as defenses against predators or as ways of killing prey.
Bewertung:In uncompetitive inhibition, the inhibitor binds only to the enzyme-substrate complex.
Bewertung:A protein kinase inhibitor is a type of enzyme inhibitor that blocks the action of one or more protein kinases.
Bewertung:The herbicide glyphosate is an inhibitor of 3-phosphoshikimate 1-carboxyvinyltransferase, other herbicides, such as the sulfonylureas inhibit the enzyme acetolactate synthase.
Bewertung:Natural enzyme inhibitors can be poisons and are used as defenses against predators or as ways of killing prey.
Bewertung:In non-competitive inhibition, the binding of the inhibitor to the enzyme reduces its activity but does not affect the binding of substrate.
Bewertung:As this drug resembles the protein that is the substrate of the HIV protease, it competes with this substrate in the enzyme's active site.
Bewertung:An enzyme inhibitor hinders this process, either by binding to the active site or by binding to another site on the enzyme.
Bewertung:Some reversible inhibitors bind so tightly to their target enzyme that they are essentially irreversible.
Bewertung:An enzyme's activity decreases markedly outside its optimal temperature and pH.
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